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Open access Oct 2026

Multi-omics analysis of high-grade serous ovarian cancers reveals heterogeneity and distinct immunological patterns based upon clinico-genomic status

A spatially resolved framework identifies BRCA-associated immune transcriptional patterns in HGSOC and provides a basis for future mechanistic validation, and support a model in which BRCA mutation status is associated with functional differences within broadly conserved spatial regions, rather than extensive reorganiz...

Jing Qian, R. Bassiouni, Yu-Xin Jin et al. · 0 citations

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