The role of physical fitness in cognitive reserve and brain maintenance remains unclear. We investigated the associations of muscular and aerobic fitness (VO2max) with markers of brain health and cognition in 353 cognitively unimpaired older adults (mean age = 72.77 ± 7.95 years; 177 females). Muscular fitness compris...
S. Schwarck, N. Behrenbruch, B. Schumann-Werner et al.· npj Aging· 0 citations
Differential associations of age and AD pathology with mesoscale MTL-connectivity patterns show differential associations of age and AD pathology with mesoscale MTL-connectivity patterns, which may support memory function in the short term while contributing to subsequent memory decline.
Larissa Fischer, N. Vockert, Joseph Höpker Fernandes et al.· bioRxiv· 0 citations
Findings indicate that temporo-parietal connectivity is associated with both AD molecular pathology and, for a subset of connections, with memory performance, which may provide a link between synaptic pathology and cognitive outcomes.
Yanin Suksangkharn, B. Schott, P. Zeidman et al.· Alzheimer's Research & Thera...· 0 citations
WMH confluence is introduced as a reproducible, automated, and fine-grained measure of lesion spatial organisation that provides complementary information about morphological WMH severity beyond volume and is an alternative to visual rating scales.
Tatjana Schmidt, Robert Salzmann, M. Montagnese et al.· bioRxiv· 0 citations
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