B. Touquet

Pentachloropseudilin disrupts multiple steps of the Toxoplasma gondii lytic cycle, consistent with predicted multi-myosin engagement

The pharmacological targeting of apicomplexan myosins has emerged as a validated antiparasitic strategy, with selective inhibitors of MyoA demonstrating activity against parasite motility and invasion. However, apicomplexan parasites express multiple unconventional myosins with essential functions throughout their life...