B. Zampogna

REVIEW The role of leptin in osteoarthritis: from pathogenesis to clinical implications

Improved function and patient satisfaction with fewer residual symptoms following kinematically versus mechanically aligned total knee arthroplasty: A retrospective study from FP-UCBM Knee Study Group.

PURPOSE To compare residual symptoms, function and patient satisfaction following unrestricted kinematic alignment (KA) versus mechanical alignment (MA) in primary total knee arthroplasty (TKA). It was hypothesized that KA would reduce residual symptoms and improve function and satisfaction. METHODS A retrospective c...

Mid- to long-term follow-up of trabecular titanium acetabular cups in hip revision surgery for acetabular bone defects.

BACKGROUND Acetabular defects can be restored using different surgical techniques. Excellent results have been observed with trabecular titanium (TT) which mimic the structure of trabecular bone. The aim of our study is to evaluate the mid-to-long-term outcome in revision surgery due to severe acetabular defect using T...

Hip Osteoarthritis and the Human Microbiome: Current Concepts, Biological Insights and Future Directions.

Osteoarthritis (OA) is among the leading causes of disability worldwide, yet its pathogenesis remains incompletely understood. Once considered a "non-inflammatory" degenerative disorder, OA is now recognized as a condition driven by chronic low-grade inflammation. Emerging evidence implicates gut dysbiosis as a modifia...