Author

Bader Y. Alhatlani

2 papers indexed here

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Open access Sep 2026

Identification of natural TLR4 modulators through network pharmacology and molecular modeling in SARS-CoV-2 Acinetobacter baumannii co-infection

Viral–bacterial co-infection with SARS-CoV-2 and Acinetobacter baumannii exacerbates hyperinflammation via Toll-like receptor 4 (TLR4)-mediated immune pathways. Using network pharmacology, an integrated protein–protein interaction network identified 30 key inter-species hubs comprising viral, bacterial, and human host...

M. Ouassaf, S. U. Khan, K. R. Rengasamy et al. · Frontiers in Chemistry · 0 citations

Open access Aug 2026

DDI-HierPred: An Artificial Intelligence-Based Hierarchical PK/PD Platform for Drug–Drug Interaction Prediction

Background/Objectives: Pharmacokinetic and pharmacodynamic drug–drug interactions are major determinants of drug safety in polypharmacy, with potential consequences including reduced therapeutic efficacy, altered drug exposure, and increased adverse effects. This study presents DDI-HierPred, an artificial intelligence-...

M. Ouassaf, Bader Y. Alhatlani · Pharmaceutics · 0 citations