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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Bai-Le Zuo

h-index 9 View on Semantic Scholar

We have 2 of 21 papers

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Review Aug 2026

The niche-metabolism axis: reprogramming tumor-associated macrophages for precision immunotherapy.

This framework highlights that therapeutic paradigms should shift from nonselective TAM depletion to niche-specific metabolic-epigenetic reconstruction, providing a precise roadmap for designing next-generation engineered macrophage therapies.

Li-Jun Zhao, Xu-Yun Li, Wen-Yue Liu et al. · 0 citations
Jul 2026

p53 hotspot mutants attenuate CTL-mediated tumor cell killing through a novel ALKBH5-YTHDF3-PD-L1 pathway

It is found that the oncogenic effect of mutant p53 in vivo is dependent on the tumor immune microenvironment, and restoration of ALKBH5 activation or inhibition of the m6A modification-YTHDF3 axis could potentially reactivate immune surveillance and eliminate tumors harboring mut-p53.

Zhuan Ju, Xiang Zhang, Wen-Jie Zuo et al. · 0 citations

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