Open access
Aug 2026
Comparative systemic pathogenicity and host tropism of ancestral SARS-CoV-2, Delta, and Omicron EG.5 variants in K18-hACE2 mice
This study provides direct experimental evidence for a pronounced attenuation in pathogenicity along the evolutionary trajectory from Wild-type through Delta to Omicron EG.5.5, and offers crucial insights for risk assessment of emerging variants.
Xiaofang Peng, Qi Zhang, Pingping Zhou et al.
· Frontiers in Immunology · 0 citations