Balamurugan Sundaram

Synergistic Activation of TLR Adaptors MyD88 and TRIF Induces Inflammatory Cell Death in Infection 2260795

Severe infections often cause life-threatening inflammation, multi-organ failure, and death. During infection, pathogens carry multiple pathogen-associated molecular patterns (PAMPs) such as LPS, flagellin, nucleic acids, and lipoproteins which activate more than one pattern-recognition receptor (PRR). These PRRs...