Keap1 Deficiency Promotes Macrophage M2 Polarization and Protects β Cells
Background Progressive pancreatic β‐cell injury is a core feature of Type 2 diabetes mellitus (T2DM). Imbalance between macrophage M1 and M2 polarization, driven by chronic inflammation, is a key contributor to this injury. The Keap1‐Nrf2‐ARE pathway regulates macrophage polarization and inflammatory responses, but whe...