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Bao-Long Wang

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Open access Sep 2026

Adipose-derived mesenchymal stem cell-exosomes attenuate lipopolysaccharide-induced acute lung injury in mice by regulating the TGFBR2/Smad4 axis to suppress NLRP3-mediated macrophage M1 polarization and pyroptosis

ADMSC-derived exosomes alleviate LPS-induced acute lung injury by delivering miR-19b-3p to inhibit the TGFBR2/Smad4 signaling pathway, thereby suppressing NLRP3-mediated macrophage M1 polarization and pyroptosis and reducing lung epithelial cell apoptosis.

Jie Li, Huan Kang, Bao-Long Wang et al. · 0 citations

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