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Bao-Qing Jia

2 papers indexed here

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Open access Oct 2026

SERPINB9 Promotes Colorectal Cancer Liver Metastasis and Immunotherapy Resistance: Association With MHC‐I Downregulation and CD8 + T Cell Dysfunction

Colorectal cancer liver metastasis (CRLM) is the leading cause of mortality in colorectal cancer (CRC) patients, for which effective treatments remain limited. The mechanisms by which tumor cells evade immune surveillance and escape cytotoxic killing remain poorly understood. SERPINB9 (SB9) has been implicated in...

Xin Liu, Wen-Chen Wang, Hong-Qian Wang et al. · 0 citations
Open access Sep 2026

SFRP2 Potentiates Metastasis of Colon Cancer by Enhancing Snai1 Protein Stability via USP11

ABSTRACT Metastatic colon cancer remains a significant clinical challenge, often associated with poor patient prognosis. Recent studies have identified the secreted frizzled‐related protein 2 (SFRP2) as a key player in this malignancy, showing its overexpression in metastatic cases. This research aimed to elucidate the...

Yan-Shen Kuang, Xin Liu, Mu Ke et al. · 0 citations

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