Author

Bao-Shan Liu

3 papers indexed here

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Aug 2026

Guchang capsule alleviates inflammatory bowel disease by downregulating lncRNA THRIL and inhibiting the p38 MAPK/NF-κB signaling pathway.

BACKGROUND Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with limited treatment options. Guchang capsule (GC) has been used in traditional Chinese medicine, but its effects on IBD and the underlying molecular mechanisms remain unclear. METHODS A dextran sulfate sodium (DSS)-induced colitis model...

Xiao-Hong Wang, Rong Liu, Hong Wang et al. · Molecular Immunology · 0 citations

Review Open access Sep 2026

Immune remodeling of tumor-draining lymph nodes: mechanistic determinants of checkpoint blockade responsiveness

Remodeling of tumor-draining lymph nodes (tdLNs) can precede overt nodal metastasis and has emerged as a determinant of immune checkpoint blockade (ICB) responsiveness. Sustained lymphatic delivery of tumor-derived antigens, extracellular vesicles, cytokines, and metabolites perturbs stromal and vascular programs, incl...

Cai-Yan Jia, Shu-Xuan Li, Mu-Hua Chen et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

Emerging targeted therapies for primary immune thrombocytopenia: novel agents, combination strategies, and future directions

This article analyses recent therapeutic trials with Bruton’s tyrosine kinase inhibitors, splenic tyrosine kinase inhibitors, and neonatal Fc receptor antagonists, demonstrating an improvement in platelet counts and patients’ quality of life.

Zhen Wang, Wu-Xia Yang, Nuo Xu et al. · Frontiers in Pharmacology · 0 citations