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Aug 2026

Class I capsid assembly modulators induce potent anti-HBV activity through direct viral suppression, innate immune activation and caspase-3-independent clearance of infected hepatocytes.

Capsid assembly modulators (CAMs) are promising antiviral agents for chronic hepatitis B virus (HBV) infection. This study investigates the anti-HBV activity and immunomodulatory effects of Class I CAMs (CAM-A) in vitro and in vivo. In HepAD38 cells, CAM-A treatment significantly upregulated the expression of interfero...

Pu-Shuo Wang, Xin-Chang Liu, Yong Xie et al. · 0 citations

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