Deep Learning-Powered Spatial Transcriptomics Analysis to Predict Immune Checkpoint Inhibitor Response from Pre-Treatment Digital Pathology Slides
Response to immune checkpoint inhibitors (ICIs) is governed in part by the spatial organization of the tumour microenvironment, yet most deep learning models applied to digital pathology treat tissue regions independently and therefore do not represent the neighbourhood interactions that shape immune activation. This s...
R. Logeshwaran, Basheer Mohamed, Somnath B. Thigale et al.
· Trends in Immunotherapy · 0 citations