Author

Basil J. Greber

2 papers indexed here

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Open access Oct 2026

Cryo-tides: synthetic peptides for cryo-EM grid preparation of multi-subunit protein complexes sensitive to the air-water interface

Cryogenic electron microscopy (cryo-EM) has enabled rapid progress in structural biology throughout the last decade. However, cryo-EM sample preparation still represents a major bottleneck in high-resolution structure determination. Many proteins and macromolecular complexes interact with the air-water interface during...

Rose Young, Amy J. S. McGeoch, M. Jessop et al. · bioRxiv · 0 citations

Open access Jul 2026

Visualization of stepwise derepression of TFIIH in global genome nucleotide excision repair

High-resolution structures of three NER intermediates are determined that visualize how TFIIH arrives at sites of DNA damage in an autoinhibited state and how autoinhibition is released via previously undescribed intermediates, contributing to a mechanistic understanding of human DNA repair.

Natàlia de Martín Garrido, Callum A. F. Haste, Junjie Feng et al. · Science Advances · 0 citations