Open access
Sep 2026
Multivalent Ligand–Protein Interactions in DNA‐Confined Compartments: Role of Geometric Match and Electrostatic Screening
Multivalent interactions are widely used to enhance ligand binding to selected proteins, yet their occurrence in spatially confined nanoscale environments has been poorly investigated. Here, we use programable DNA origami nanocompartments to study multivalent interactions within nanosized volumes. In our system, encaps...
Sabrina Gambietz, Pierre Stegemann, A. Jaekel et al.
· Small Structures · 0 citations