Review
Open access
Sep 2026
High-grade gliomas where resources define survival: a systematic review and meta-analysis of outcomes, surgical access, and molecular diagnostic gaps in low- and middle-income countries
High-grade gliomas remain among the most aggressive tumors in neuro-oncology. Although prognosis is strongly influenced by tumor biology, survival in low- and middle-income countries is also shaped by health-system factors, including delayed diagnosis, limited surgical infrastructure, incomplete adjuvant therapy, a...
C. Castillo-Rangel, Gervith Reyes Soto, Edinson David Berrío Perea et al.
· Frontiers in Oncology · 0 citations