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Sep 2026

Distinct Active-Site Dynamics of Primitive Catalytic Amyloids Revealed by Two-Dimensional Infrared Spectroscopy

Catalytic amyloids are proposed evolutionary precursors of modern enzymes, yet the active-site dynamics underlying their distinct catalytic properties remain unclear. Here, we combine azide infrared probes and two-dimensional infrared (2D-IR) spectroscopy to characterize the active-site dynamics of primitive catalyti...

Zhi-Yuan Zhao, Qin Zhang, Bing-Yao Wang et al. · 0 citations

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