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Author

Beilei Shi

2 papers indexed here

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Open access Sep 2026

Nuciferine Ameliorates Ovariectomy-Induced Bone Loss via TFEB-Mediated Autophagy-Lysosomal Pathway

Background: Postmenopausal osteoporosis is a common metabolic bone disease that leads to reduced bone formation and increased fracture risk. Nuciferine, an aporphine alkaloid from the lotus leaf, can regulate the TFEB-mediated autophagy-lysosomal pathway. This pathway is critical for osteogenic differentiation. However...

Bei-Lei Shi, Ze Gao, Shih-Yu Chen et al. · 0 citations
Review Open access Jul 2026

Medicine–food homologous bioactives in metabolic dysregulation-associated osteoporosis: a review of preclinical evidence and potential liver–bone and gut–bone actions

Osteoporosis is increasingly linked to metabolic dysregulation. Medicine–food homologous (MFH) materials contain diverse natural bioactives with reported osteoprotective effects, but their overall evidence landscape remains insufficiently integrated. To synthesize preclinical evidence on MFH-derived bioactives that imp...

Wen Fan, Beilei Shi, Ze Gao et al. · 0 citations

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