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Author

Ben Murrell

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Open access Sep 2026

Datamonkey 3: browser-native molecular evolution analysis

We present Datamonkey 3, a browser-native implementation of the Datamonkey web platform for molecular evolutionary analysis. By utilizing WebAssembly to execute the HyPhy analysis engine on the client side, Datamonkey 3 removes the dependency on remote computational clusters for standard analyses. This architecture ens...

Steven Weaver, Ben Murrell, Anton Nekrutenko et al. · 0 citations
Open access Aug 2026

The physicochemical basis of protein evolution: property-informed evolutionary models (PRIME)

PRIME (PRoperty Informed Models of Evolution), a framework of codon-level maximum likelihood methods that explicitly model amino acid exchangeability as a function of physicochemical properties, provides a useful framework for characterizing the mechanistic drivers of protein diversity.

Hannah Kim, Konrad Scheffler, Anton Nekrutenko et al. · 0 citations

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