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Benjamin A. R. Bekkema

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Open access Sep 2026

Human NEU3 and NEU4 enzymes prefer short polysialic acid substrates.

Regulation of sialic acids is important to many biological processes and involves both biosynthesis and catabolism. The human neuraminidase enzymes (hNEU) regulate many sialosides in human health and disease. Polysialic acid (polySia) is a polyanion of α(2 → 8) linked sialic acids with roles in nervous, reproductive, a...

Carmanah D. Hunter, Benjamin A. R. Bekkema, Christopher W. Cairo · 0 citations

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