Benjamin Kroeger

The mechanosensitive protein Zyxin influences Hippo signaling and tissue growth via adherens junctions and basal spot junctions in Drosophila.

Mechanical forces such as tension and compression play a central role in the growth and morphogenesis of tissues. Cell-cell junctions and the actin cytoskeleton are key mediators of mechanical forces and influence the activity of signaling networks, including the Hippo pathway. Here, we show that the mechanosensitive p...

SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry