Benjamin L. Weinberg

Surface architecture of the bacterial envelope determines phage adsorption route in pathogenic Escherichia coli O157:H7

This study provides the first genome-scale, functional genetic map of phage susceptibility determinants in O157:H7 and demonstrates that the state of the outer surface layers, specifically the O-antigen and the gfc-etk capsule, determines whether phages can reach conserved terminal receptors.