We present an active mixing toolhead for extrusion bioprinting. The tool enables the programmable fabrication of tumor microenvironment gradient arrays, through controlled deposition of mixed hydrogel precursor formulations into 384-well plates, pre-seeded with tumor cells. It operates on an open-source bioprinter and...
Marie Moulin, E. Sehic, Adam Engberg et al.· bioRxiv· 0 citations
Spider silk protein (spidroin)-based hydrogels from the recombinant miniature spidroin NT2RepCT mixed with VN-NT, a vitronectin peptide fused to the spidroin N-terminal (NT) domain are established as non-toxic substrates with adjustable mechanics and straightforward, modular functionalization with bioactive motifs and...
S. Korpela, U. Chatterjee, G. Greco et al.· Small· 0 citations
The formulation of a cytocompatible buffer system optimized for mini-spidroin hydrogels improves transparency and accelerates gelation, while maintaining experimental simplicity, thereby advancing the utility of mini-spidroin hydrogels as cell culture platforms.
S. Stadlmayr, Tove Kivijärvi, B. Gross et al.· Communications Materials· 1 citation
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