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Author

Betul Orcan-Ekmekci

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Preprint Aug 2026

BioKERN: Biological Kernel Regularization for Histology-to-Transcriptomics Neighborhood Retrieval

Spatially resolved biology requires representations that preserve biological neighborhood structure rather than only exact cross-modal correspondences. Existing histology--transcriptomics objectives can emphasize instance-level matching even when non-paired spots share molecular or spatial context. We introduce BioKERN...

S. Cho, Betul Orcan-Ekmekci · 0 citations

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