Bhagya Jyothi J. L

Inhibition of Mycobacterium tuberculosis β-Lactamase BlaC with Natural Products: An Integrated Computational Study

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains the second leading cause of infectious disease-related mortality worldwide. Resistance to β-lactam antibiotics is largely attributed to the chromosomally encoded BlaC β-lactamase, which hydrolyzes commonly used β-lactam drugs. Although inhibitors such...