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Author

Bhargav Shreevatsa

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Review Open access Sep 2026

Silencing with precision: In silico strategies for antisense oligonucleotide engineering

The state of the art in in silico tools and methods that are used for the design, 3D structural prediction, molecular docking, and simulation of ASOs, including their applications and limitations are summarized.

Abhigna Nagaraj, C. Kavana, Bhavana Harendra et al. · 0 citations
Open access Aug 2026

7-Deshydroxypyrogallin-4-carboxylic acid dietary phytochemical as a putative FTO inhibitor in breast cancer: an integrated computational and cytotoxicity study.

These findings provide a preliminary mechanistic and experimental framework for DCA as a dietary FTO inhibitor in breast cancer, necessitating further validation through orthogonal target engagement assays, m6A quantification, and in vivo tumor models.

Shuaib Pasha, S. Harishkumar, Revanth Handralu Chandraiah et al. · 0 citations

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