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Bhavin A. Vyas

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Open access Sep 2026

Engineered polymeric nanosponge in-situ gel enables sustained and enhanced nose-to-brain delivery of quetiapine fumarate.

Quetiapine fumarate is a second-generation antipsychotic with limited oral bioavailability owing to extensive hepatic first-pass metabolism, making it a suitable candidate for intranasal brain delivery. This study aimed to develop a quetiapine fumarate-loaded nanosponge in-situ gel for sustained and enhanced brain deli...

Priyanshi R. Patel, Aashka H. Bhatt, Hetal P. Patel et al. · 0 citations

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