Ergothioneine as a diet-derived xenobiotic: OCTN1-mediated disposition, mitochondrial redox regulation, and emerging implications for cardiovascular disease.
Mitochondrial dysfunction is a convergent upstream driver of cardiovascular disease, linking energetic failure, oxidative stress, inflammation, and maladaptive remodelling.The inconsistent results of conventional antioxidant trials are likely to be the result of multiple factors, including compound selection, dose and...