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Bhupendra G. Prajapati

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Review Open access Oct 2026

Beyond the Needle: Transforming Traditional Healthcare with Microneedle Drug Delivery Systems

In the present era, modern drug delivery systems play a fundamental role in ensuring the systematic delivery of the drug into the body, reaching the desired targets. Across recent decades, the drug delivery system has evolved from simple oral and injectable formulations to interpolating with various developed technique...

Arjun Gokulan Manivannan, Narayanan Jayasankar, V. Kashid et al. · 0 citations
Review Open access Aug 2026

Liposomal Delivery of Hepatoprotective Phytochemicals for Liver Diseases: Advances in Formulation, Targeted Delivery, and Clinical Translation

Background/Objectives: Chronic liver diseases (CLDs), including viral hepatitis, alcohol-related liver disease, non-alcoholic fatty liver disease, hepatic fibrosis, and hepatocellular carcinoma, account for approximately two million deaths annually and remain a global health challenge. Although phytochemicals exhibit a...

D. Khunt, Jigna Khasiya, Sanjay Chauhan et al. · 0 citations
Review Sep 2026

Hydrogel-Based Nanocarriers: Novel Strategies for Atopic Dermatitis Treatment

Atopic dermatitis is a chronic inflammatory skin disease that requires repeated drug delivery to achieve a therapeutic effect. Traditional formulations, such as creams and ointments, are constrained by inadequate penetration, residence time, and low systemic absorption. This review discusses the development of nanocarr...

Megha Patil, Shagun Rangra, Denisha Gadhiya et al. · 0 citations
Review Open access Aug 2026

Hydrogel-based smart bioinks for 3D bioprinting: design strategies and applications in brain tissue engineering and tumor microenvironment modelling

Smart bioinks based on hydrogel have emerged a revolutionary platform in three-dimensional bioprinting that facilitates the development of biomimetic tissue constructs with a higher level of structural and biological precision. These advanced bioinks exhibit dynamic responsiveness to physicochemical and biological stim...

C. Aundhia, Jagruti Desai, Swayamprakash Patel et al. · 0 citations
Open access Oct 2026

Hydrogel Stabilised Nanostructured Lipid Carrier Fortified Triamcinolone Acetonide for the Management of Atopic Dermatitis.

Atopic dermatitis (AD) is a long-term skin disease that causes redness, itching, and a loss of skin barrier function, which sometime shows significant effect on a person's quality of life. In this study nanostructured lipid carrier (NLCs)-based hydrogel was fabricated for the topical delivery of triamcinolone acetonide...

Gajanan S. Shinde, Himanshu Paliwal, A. K. Singh et al. · 0 citations
Review Open access Aug 2026

Ethosomal drug delivery systems for skin cancer: Mechanistic insights, formulation strategies, and translational challenges

Introduction: Skin cancer is one of the most prevalent malignancies worldwide, with incidence increasing by approximately 2–3% annually due to prolonged ultraviolet radiation exposure, genetic predisposition, and an ageing population. Conventional treatments, including oral, injectable, and topical therapies, are often...

Bhupendra G. Prajapati, O. Alsaidan, Sami I. Alzarea et al. · 0 citations
Review Open access Aug 2026

Epigenetic Control of Stress-Induced Depression: Emerging Roles of HDAC3 and HDAC6

Major depressive disorder (MDD) is a heterogeneous psychiatric disorder characterized by impaired mood, neuroplasticity, neuroinflammation, and dysregulated stress response systems. Chronic stress can induce epigenetic changes leading to depression. Evidence suggests that histone acetylation and deacetylation are epige...

Arathy S. Mohan, Narayanan Jayasankar, V. Kashid et al. · 0 citations
Review Open access 2026

Customized multifunctional nanocarriers for cancer therapy: Integrating targeting, imaging, and combination treatment for diverse patient needs

Major nanocarrier platforms are examined, with particular emphasis on their tunable physicochemical properties and modular architectures that facilitate adaptation to diverse patient populations, including elderly patients and those with treatment-resistant conditions.

Devesh U. Kapoor, Anil Pareek, Jigal Hirawala et al. · 0 citations
Review Open access Aug 2026

Smart Mesoporous Silica Nanoparticle-Based Drug Delivery Systems: Recent Advances in Biomedical Applications, Wound Healing and Therapeutic Perspectives

This review highlights MSN-based drug delivery systems in cancer therapy, where multifunctional nanocarriers enable site-specific delivery, controlled drug release, enhanced tumor accumulation, and reduced off-target effects.

Manickam Rajkumar, N. Prathap, V. Kashid et al. · 0 citations

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