Author

Bi-yi Zhao

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Oct 2026

Bushen Huoxue Formula promotes osteoporotic fracture healing by CGRP-mediated dual regulation of BMSCs-osteoclasts balance through modulating mitochondrial energy metabolism.

Osteoporotic fracture (OPF) is a serious complication that severely impairs the quality of life. Bushen Huoxue Formula (BHF), a clinically established prescription based on the TCM principle of "tonifying the kidney and activating blood circulation," has been widely used to treat osteoporosis. However, its efficacy in...

Qing Lin, Bi-Yi Zhao, Zhu-Xuan Liu et al. · Phytomedicine · 0 citations

Open access Jul 2026

Shared Genetic Architecture Between Epigenetic Aging and Musculoskeletal Diseases

The results support a prioritized genomic map with substantial instrument- and model-specific uncertainty, and disease-to-clock signals were richer than clock-to-disease signals, GrimAA shared polygenic architecture with osteoarthritis, and selected loci showed strong shared-variant evidence.

Wei Xu, Xuan-Yu Zhang, Bi-yi Zhao et al. · Genes · 0 citations