Author

Biao Ruan

1 paper indexed here

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Open access Aug 2026

PAX3 deficiency is associated with NLRP3-related inflammatory signaling and hearing loss in a mouse model of Waardenburg syndrome

Findings support a model in which PAX3 deficiency is associated with melanocyte-lineage dysfunction, impaired strial homeostasis, and activation of an NLRP3-related inflammatory pathway.

Mengxue Zhu, Tao Lu, Min Guo et al. · Orphanet Journal of Rare Dis... · 0 citations