Bidhan Koirala

A single-antigen, multi-epitope subunit vaccine candidate against lumpy skin disease virus designed by conservation-guided reverse vaccinology

Lumpy skin disease virus causes devastating economic losses in cattle, and current live attenuated vaccines carry risks of reversion and cannot differentiate infected from vaccinated animals. We applied conservation-guided reverse vaccinology (vaccine design from genomic sequence data) to identify conserved epitopes (i...