Author

Bifei Zhang

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Open access Jul 2026

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

It is found that the hyperlactate microenvironment induced by abnormal glycolysis in WT significantly upregulates the level of histone H3K18 lactylation (H3K18la), which promotes WT cell proliferation and migration.

Yanping Wang, Hongjie Gao, Bifei Zhang et al. · Advancement of science · 0 citations