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Bilal Hoblos

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Review Open access Aug 2026

Structured HTE Data and Integrated Bayesian Optimization Accelerate Scalable Amidation Process Development

We describe the evolution of our early hit-identification workflow for reagent-mediated amidation reactions in support of commercial route development. Over the past decade, our strategy progressed from broad, exhaustive high-throughput experimentation (HTE) with limited data maturity to a modern, enterprise-scale digi...

Jason M. Stevens, Dung L. Golden, Nicola A. Dare et al. · 0 citations

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