Integrative Bioinformatics and Exploratory Experimental Validation of Expression Changes in miR-214-3p, miR-1b, miR-133b-3p, and Directionally Concordant mRNAs in a Rat Model of Acute Myocardial Infarction
Background and Objectives: Acute myocardial infarction (AMI) induces inflammatory, cell-death, and fibrotic responses. MicroRNAs modulate these processes by regulating specific mRNA targets, but the contribution of individual miRNA–mRNA axes remains incompletely defined. Materials and Methods: Transcriptomic datasets G...