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Dormancy and reactivation of disseminated tumor cells: From molecular mechanisms to therapeutic implications.
A comprehensive theoretical framework and intervention strategies to delay or prevent tumor recurrence and metastasis are provided, aiming to provide a comprehensive theoretical framework and intervention strategies to delay or prevent tumor recurrence and metastasis.
An RCA-Coupled CRISPR/Cas12a Cascade-Enhanced SERS Platform for Ultrasensitive Detection of Exosomal miRNA-21 in Colorectal Cancer Serum
Purpose Ultra-sensitive detection of exosomal miR-21 is crucial for the early diagnosis of colorectal cancer. This study aims to develop a cascade amplification platform based on surface-enhanced Raman scattering (SERS), combining rolling circle amplification (RCA) and CRISPR/Cas12a, to enable ultra-sensitive quantitat...