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Author

Bin Hou

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Open access Oct 2026

Reversal of Chronic Stress‐Induced Inflammaging by Bazi Bushen Formula Through AMPK‐Sirtuins Axis Activation and Myeloid Reset

ABSTRACT Chronic stress potentially accelerates aging and increases age‐related disease risk. However, the underlying mechanisms and organ specificity remain unclear. Utilizing a 12‐month unpredictable chronic mild stress (UCMS) mouse model, we revealed chronic stress significantly exacerbates systemic inflammation, ca...

Meng-Nan Li, Zhe-Ming Chen, Lu Wang et al. · 0 citations
Review Open access Aug 2026

Emerging microbiome–mitochondria crosstalk in host defense and infectious diseases: mechanistic insights into NLRP3 inflammasome activation and mtDNA-mediated immunomodulation

These investigations emphasize the emerging mechanistic significance of microbiota-induced modulation of mitochondrial function in host defense mechanisms, thereby illuminating potential therapeutic approaches that focus on microbial composition, mitochondrial dynamics, and inflammasome signaling to alleviate infectiou...

Xinxing Lu, Wenbin Sun, Daowei Zhang et al. · 1 citation

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