Open access
Sep 2026
CAF-derived BHB modulates FXR1-Kbhb and NK-cell lipid metabolism in osteosarcoma
Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents and is characterized by high aggressiveness and poor prognosis. Although surgery and chemotherapy have improved overall survival, outcomes for relapsed or metastatic disease remain extremely poor, thus underscoring the urgent...
Yi-Han Yu, Wei Wu, An-Zhen Ju et al.
· International Journal on Bio... · 0 citations