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Review Open access Sep 2026

Effects of exercise and physical activity on circulating inflammaging- and immunosenescence-related biomarkers in older adults and adults with chronic diseases: an umbrella review

Exercise and physical activity may produce small reductions in some circulating inflammatory biomarkers, most consistently TNF-alpha and CRP, but effects on IL-6 are inconsistent, and certainty is very low.

Guang-Wei Chai, Jin-Hong Xue, Bin Xie · 0 citations

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