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Sep 2026

Evolutionary Rewiring of Sugar Transporter Gene manXYZ Enables Highly Coordinated Non-glucose Metabolisms in Engineered Lactic Acid Bacterium

Achieving highly coordinated metabolism and efficient conversion of lignocellulose-derived non-glucose sugars remains a major challenge for biorefinery microbial cell factories. Herein, we report an evolutionary rewiring of an engineered lactic acid bacterium Pediococcus acidilactici G1 with enhanced co-utilization o...

Jiao Liu, Ni-Ling He, Yi Zhang et al. · 0 citations
Sep 2026

Improved xylose utilization and ethanol fermentation performance with ultracentrifugation-assisted adaptive evolution of Saccharomyces cerevisiae.

Saccharomyces cerevisiae is the most widely used microorganism for industrial ethanol fermentation, but its limited xylose assimilation capacity remains a major bottleneck for efficient cellulosic ethanol production. In this study, repeated ultracentrifugation was incorporated as a physical perturbation into an adaptiv...

Zhuo-Lin Song, Jia-Shu Bao, Tao Han et al. · 0 citations

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