Bin-Zhi Liao

Genome-wide association study of sarcopenia index reveals sex-stratified genetic architecture

The sarcopenia index (SI), defined as the ratio of serum creatinine to cystatin C, is a proposed biomarker of muscle mass and sarcopenia, yet its genomic basis and genetic architecture remain largely unexplored. We performed combined-sex and sex-stratified genome-wide association studies of SI in the UK Biobank. We exa...