Trametes versicolor, a traditional medicinal fungus in China, shows broad application prospects in modern medicine and the health industry. T. versicolor polysaccharopeptides (TVPPs) are among its core bioactive constituents and exhibit notable pharmacological activities in immunomodulation, antitumor, antiviral, anti-obesity, and hepatoprotective effects; their biological functions and application value have attracted considerable attention. At present, the extraction and structural characterization methods for TVPPs become relatively mature. Different TVPPs contain high levels of glucose and acidic amino acids, and these structural characteristics are closely related to their functional performance. Although existing studies have conducted preliminary analyses the chemical structures, they remain insufficient to systematically elucidate correlation between molecular structure and biological function. The review provides a comprehensive overview of recent developments in research on TVPPs, focusing on their extraction processes, chemical features, bioactivity, and their intrinsic relationships, and provides prospects for future research directions and industrial applications, with the aim of offering comprehensive theoretical references and technical support for subsequent related studies.
Zheng Zhang, Yahuan Wang, Haoxiang Lu et al.· International Journal of Bio...· 0 citations
Chemical insecticides remain a cornerstone of contemporary integrated pest management (IPM). However, the toxicological profile of Streltzoviella insularis, an economically important wood-boring pest, remains insufficiently characterized. In this study, a laboratory rearing system for S. insularis was established using a customized artificial diet, providing a reliable platform for toxicological assays. Bioassays indicated that chlorantraniliprole (CAP) exhibited significantly higher insecticidal activity against fifth-instar larvae than the three other insecticides tested. Focusing on disruption of gut bacterial symbiont homeostasis as a mechanistic entry point, we investigated whether sublethal CAP exposure imposes fitness costs on S. insularis through perturbation of gut symbiotic communities. 16S rRNA amplicon sequencing revealed substantial restructuring of the larval bacterial community under sublethal CAP stress. The abundance of the core genus Enterococcus was significantly reduced, whereas Carnimonas and Levilactobacillus were significantly enriched. These three taxa came to dominate the reshaped gut microbiota, suggesting a potential compensatory functional shift following depletion of core symbionts. Activities of key digestive enzymes, including α-amylase, lipase, and trypsin, were significantly reduced. Substantial fitness costs were observed, including reduced larval and pupal weights, prolonged larval development time, and decreased pupation success, adult emergence, egg hatching, and female fecundity. Collectively, these findings suggest that sublethal CAP exposure is closely associated with gut symbiont dysbiosis in S. insularis, accompanied by impaired digestive function and delayed larval growth and development.
Ze-Feng Li, Yang Zhao, Bing Bi et al.· Journal of insect physiology· 0 citations
