Sep 2026
Modulating nanoconfined space charge for PCR-free and bisulfite-free detection of cfDNA methylation in ovarian cancer.
A bisulfite-free and PCR-free electrochemical nanochannel biosensor that modulates nanoconfined space charge to directly translate discrete epigenetic marks into measurable ion flux is reported, demonstrating great translational potential for precise epigenetic liquid biopsy.
Kai Hu, Zi-Meng Zhang, Bing-Heng Li et al.
· Biosensors & bioelectronics · 0 citations