Aug 2026
DPF3a couples H3K36me2-dependent chromatin remodeling to genome architecture during myogenesis
The findings uncover a non-canonical mechanism whereby a chromatin remodeler regulates transcription primarily through three-dimensional genome organization rather than local accessibility control, and establish histone modification-guided chromatin remodeling as a key principle in gene regulation.
Ming Yu, Jingdong Xue, Qi Zhang et al.
· bioRxiv · 0 citations