Zearalenone exposure is associated with increased tumor burden and coordinated host-microbiota-metabolic alterations in colitis-associated colorectal cancer.
Zearalenone (ZEN) is a common foodborne mycotoxin with intestinal toxicity, but its role in colitis-associated colorectal cancer (CAC) remains unclear. This study evaluated the association between ZEN exposure and CAC progression and explored the related molecular, microbial, and metabolic alterations. Network toxicolo...