Klebsiella pneumoniae is a major cause of multidrug-resistant and hypervirulent infections worldwide, highlighting the urgent need for host-directed therapeutic strategies that complement conventional antibiotics. Emerging evidence suggests that K. pneumoniae promotes intracellular persistence by suppressing host SUMOy...
The need for cross-sectoral collaboration, innovation, and global policy coherence to mitigate AMR in aquaculture and safeguard food, environmental, and public health security is focused on.
Avani Anu Geetha, M. Soorej, Elishia Alex et al.· International Journal of Mol...· 0 citations
The mammalian immune system has evolved in constant dialogue with its diverse microbiota, forming an ecological and molecular partnership that is fundamental to health. This review examines how microbial communities shape immunity across developmental and functional axes, the immunological consequences of dysbiosis dur...
P. Babu, V. Prakash, Suja Subhash et al.· Frontiers in Cellular and In...· 0 citations
This review delineates how bacterial pathogens both induce excessive NET formation, driving endothelial dysfunction, and evade NET-mediated antimicrobial defense and critically examines the signaling crosstalk between the NET formation with other cell death pathways, particularly focusing on the ROS-mediated PAD4-RIPK...
Shwetha Susan Thomas, Geetha B. Kumar, Bipin G. Nair et al.· Frontiers in Immunology· 0 citations
This review critically examines the current landscape of AI applications in vaccine development, with particular emphasis on recent advancements, translational challenges, and the prospective role of AI in shaping the future of immunization science.
Sastha N. Kumar, Rajhans Gondane, Shubham Mahindrakar et al.· Frontiers in Cellular and In...· 1 citation
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