Open access
Sep 2026
A systematic transcriptomic atlas and predictive framework for metabolite-driven T cell state transitions
Summary Gut microbial and endogenous metabolites are key regulators at the interface of host metabolism and immunity, yet their global effects on human T cell states remain poorly defined. Here, we profile primary human T cell responses to 364 endogenous and microbiota-derived metabolites using high-throughput digital...
Yi-Yang Xu, Yi-Heng Zhao, Si-Zhe Yang et al.
· iScience · 0 citations