Author

Bo Li

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Open access Oct 2026

Control of Helix Screw-Sense Preference in Dynamic Foldamers of meso Symmetry Built From Chiral Monomeric Units.

Meso oligoureas are dynamic hydrogen-bonded foldamers capable of reversible helix polarity inversion but have so far been limited to symmetrical meso-cyclohexane-1,2-diamine monomeric units, limiting both sequence diversity and structural modification. Here, we report the synthesis and characterization of meso and "nea...

N. Gupta, Mégane Bornerie, Bo Li et al. · Angewandte Chemie · 0 citations

Open access Aug 2026

Downsizing the Histone H3–H4 Quaternary Structure Into Foldamer Mimetics Yields High‐Affinity and Cell‐Permeable Ligands of ASF1

Results show that peptide‐oligourea foldamers can reproduce the structural features of a protein quaternary structure surface, combining high affinity, high stability and cell permeability.

Bo Li, M. Perrin, E. Maillard et al. · Angewandte Chemie · 0 citations