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Author

Bo Li

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Open access Sep 2026

Identification of benzoxazine scaffold derivatives as novel CDK4 inhibitors for the treatment of cancer

Mechanistic investigations revealed that 8j induces G1 phase cell cycle arrest and promotes apoptosis, which was corroborated by the observed concentration-dependent downregulation of key cell cycle regulators, including CDK4 and cyclin D1.

Chao Lin, Shao-Feng Sun, Hua-Teng Zhang et al. · 0 citations
Review Sep 2026

Targeting the choroidal neovascularization microenvironment: new perspectives in nanotherapeutic strategies.

An in-depth exploration of advanced nano-therapeutic strategies designed to multi-target angiogenic pathways, dynamically manipulate reactive oxygen species, disrupt hypoxia-driven feedback loops, reprogram the immunoinflammatory network, and restore defective cellular autophagy are provided.

Xiao-Yan Lu, Bo Li, Bao-Yuan Sun et al. · 0 citations
Review Aug 2026

[Advances in stem cell and exosome-based therapies for dry eye disease].

This review summarizes recent advances in stem cell and exosome-based treatments for dry eye disease and analyzes their current regulatory landscapes, intending to serve as a reference for investigators within the field.

Hua-Teng Zhang, Lei-Qing Wang, Chao Lin et al. · 0 citations

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